Erythrocytosis has been reported as a potential effect of testosterone, which could be beneficial in sufferers with anemia. The best risk of erythrocytosis happens with injectable types of testosterone in contrast with transdermal preparations, especially in supraphysiologic doses. An improve of as much as 44% of the baseline hematocrit has been reported .
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We report a case of an acute ST-segment elevation myocardial infarction in a affected person with traditional cardiac risk factors using supraphysiologic doses of supplemental, intramuscular testosterone. In addition, this affected person additionally had polycythemia, likely secondary to high-dose testosterone. The patient underwent profitable percutaneous intervention of the best coronary artery. Physicians and patients ought to be conscious of the scientific consequences of anabolic steroid abuse. Development of an atheromatous plaque perpetuates endothelial dysfunction and promotes platelet aggregation and intracoronary thrombus formation (Ajayi et al 1995; Nieminen et al 1996).
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Rhoden EL, Morgentaler A. Risks of testosterone-replacement therapy and recommendations for monitoring. Testosterone replacement in hypogonadal males with angina improves ischaemic threshold and quality camsodacom of life. Ajayi AAL, Mathur R, Halushka PV. Testosterone increase human platelet thromboxane A2 receptor density and aggregation responses.